A Study Evaluating The Safety, Efficacy and Pharmacokinetics Of Ipatasertib In Combination With Atezolizumab And Docetaxel In Metastatic Castration-Resistant Prostate Cancer (mCRPC).
PHASE1
A study evaluating the safety, preliminary efficacy and pharmacokinetics of...
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
PHASE2
This phase II trial studies how well chemotherapy before surgery and radiat...
Status
Active Not Recruiting
Location
University of Arizona Cancer Center-Orange Grove Campus
Study to Evaluate Adverse Events and Change in Disease Activity When Intravenously (IV) Infused Livmoniplimab is Used in Combination With IV Infused Budigalimab in Adult Participants With Urothelial Carcinoma (UC)
PHASE2
Urothelial carcinoma (UC) is the ninth most common cancer type worldwide. W...
A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer
PHASE3
This is a Phase IIIb, multinational, multicenter, randomized, open-label st...
Status
Completed
Location
Centro de Investigaciones Médicas y Desarrollo LC S.R.L
A Study to Investigate the Tolerability of Subcutaneous (SC) Trastuzumab Administration in Participants With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Early Breast Cancer (eBC) Using Either a Single-Use Injection Device or Manual Administration
PHASE3
This multicenter study in participants with HER2-positive eBC will investig...
Status
Completed
Location
State Inst N.N. Alexandrov Republican Scientific & Practical Centre of Oncology & Medical Radiology
A Dose-escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of GDC-0032 in Combination With Docetaxel or With Paclitaxel in Patients With HER2-negative Locally Recurrent or Metastatic Breast Cancer or Non-small Cell Lung Cancer
PHASE1
This is an open-label, multicenter, dose-escalation study designed to asses...
Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors
PHASE1
The primary purpose of this study is to assess the effect of multiple-dose ...
Carboplatin and Paclitaxel With or Without Bevacizumab Compared to Docetaxel, Carboplatin, and Paclitaxel in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Carcinoma (Cancer)
PHASE1
This phase I trial is studying the side effects and best dose of intraperit...
Status
Completed
Location
University of California Medical Center At Irvine-Orange Campus